無熱原是什麼意思?

General 更新 2024-11-27

如何無菌無熱原

無菌sterility是指在任一指定的物體、介質或環境中無任何活的微生物。

Refers to any given object, medium or environment, without any living organisms.

除菌：使用物理、化學滅菌法Using physical, chemical sterilization and Asepticmethod如：0.22μm的微孔濾膜除菌、使用消毒劑、防腐劑。無菌操作法。0.22μm microporous membrane, the use of disinfectants and preservatives.

熱原pyrogen

是指夠致熱的微生物的屍體及其代謝產物，即微生物的一種內毒素，是由磷脂、脂多糖和蛋白質所組成的複合物，脂多糖是主要成分，具有特別強的熱原活性。

Ref撫rs to the bodies of Microorganisms and its metabolites that can cause fever, that is a kind of micro-organisms endotoxin, which is a kind of complex composed of phospholipids LPS and protein, LPS is a major component, with particularly strong pyrogen activity.

熱原具耐熱性、濾過性、水溶性、不揮發性、被吸附性。

去除熱源：高溫法、酸鹼法、吸附法、離子交換法、凝膠過濾法、反滲透法。活性碳常溫吸附

High-temperature method, pH, adsorption, ion exchange, gel filtration, reverse osmosis. Activated carbon adsorption at room temperature

除氧，儘量減少藥物與空氣的接觸，在配液和灌封中通入惰性氣體，常用高純度的氮氣和二氧化碳。(2)加抗氧劑。(3)調節溶液pH在最穩定pH範圍。(4)加金屬離子絡合劑。

Oxygen, drugs to minimize contact with air, in communication with fluid and potting ininert gas, commonly used in high-purity nitrogen and carbon dioxide. (2) plusantioxidants. (3) adjusting the solution pH in the most stable pH range. (4) with metalion complexing agent.

參考資料：微生物書

不開心是什麼意思

不高興，不快樂，不舒服。